Batimastat - CAS# 130370-60-4 (SHR-3162) (E)-Daporinad (FK866) prevents the [Ca2+]i

(E)-Daporinad (FK866) prevents the [Ca2+]i increase induced by different mitogens and reduces the Ca2+ content of TG-responsive Ca2+ stores in Jurkat and in activated PBLs

leading to their malformation and Hedgehog signaling blockade

CAS Number: 929007-72-7

TA 02 and SB203580 reduce the nuclear TCF/LEF-1 driven transcription of luciferase similar to DKK-1

A novel Wnt pathway inhibitor

Batimastat - CAS# 130370-60-4 (SHR-3162) (E)-Daporinad (FK866) prevents the [Ca2+]iBatimastat, CAS No. 130370 60 4, is a synthetic matrix metalloproteinase inhibitor that has shown antineoplastic and antiangiogenic activity in various tumor models. Matrix metalloproteinases (MMPs) are thought to play a significant role in tumor invasion and metastasis as well as angiogenesis. Batimastat, also known as BB 94, acts as an inhibitor of metalloproteinase activity by binding the zinc ion in the active site of MMPs. Product information CAS